Thyroid Nodule Testing

Thyroid Nodules: When & How to Get Tested

Thyroid nodules are surprisingly common, affecting up to 50% of adults, though most are benign. Getting the right tests can provide peace of mind and catch any issues early when treatment is most effective.

Quick Facts

  • What it is: Small lumps or growths that form within the thyroid gland
  • Key tests: Thyroid ultrasound, TSH, T3/T4, thyroglobulin, fine needle biopsy
  • Who should test: Anyone with neck lumps, family history of thyroid cancer, or radiation exposure
  • Cost: $79-$95 for initial blood work, imaging may cost more

Understanding Thyroid Nodules

Thyroid nodules are small growths that develop within your thyroid gland, located at the base of your neck. While the word “nodule” might sound alarming, the vast majority are completely harmless. In fact, many people have thyroid nodules without ever knowing it.

These growths can be solid, filled with fluid, or a combination of both. Most nodules are too small to feel, but larger ones may be noticeable as a lump in your neck. Some nodules can affect hormone production, while others remain completely inactive.

The key is distinguishing between benign nodules and the small percentage that could be cancerous. Early detection through proper testing gives you the best outcomes and peace of mind.

Risk factors include being female, having a family history of thyroid disease, previous radiation exposure to the head or neck, and iodine deficiency. Age also plays a role, with nodules becoming more common as we get older.

Symptoms to Watch For

  • A visible lump or swelling in your neck
  • Difficulty swallowing or feeling like something is stuck in your throat
  • Hoarseness or changes in your voice
  • Neck pain or tenderness
  • Rapid heartbeat or heart palpitations
  • Unexplained weight loss or gain
  • Feeling anxious, jittery, or unusually tired
  • Changes in bowel habits or menstrual cycles

Recommended Tests

The best approach to thyroid nodule testing combines blood work with imaging. Blood tests check your hormone levels and tumor markers, while ultrasound imaging shows the size, shape, and characteristics of any nodules.

Start with thyroid function tests including TSH, Free T3, and Free T4 to see if your thyroid is working properly. Thyroglobulin and thyroglobulin antibodies can provide additional information about nodule activity.

If blood tests suggest nodules, your doctor will likely recommend a thyroid ultrasound. This painless imaging test can detect nodules as small as 2-3 millimeters and help determine if a biopsy is needed.

Where to Get Tested

Several trusted testing services offer comprehensive thyroid panels that can detect signs of nodules. These labs provide fast, accurate results without requiring a doctor’s visit first.

HealthLabs
★★★★☆ 4.8
Lab Visit · $79 · 1-2 days

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Quest Health
★★★★☆ 4.6
Lab Visit · $89 · 1-3 days

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Labcorp OnDemand
★★★★☆ 4.5
Lab Visit · $95 · 1-2 days

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Understanding Your Results

Normal TSH levels typically range from 0.4 to 4.0 mIU/L, though optimal levels may be narrower. If your TSH is outside this range, it could indicate your nodules are affecting hormone production.

Elevated thyroglobulin levels might suggest nodule activity, especially if you’ve never had thyroid surgery. However, results must always be interpreted alongside your symptoms and medical history.

Remember that abnormal results don’t automatically mean cancer. Most thyroid nodules are benign, and many can be monitored rather than immediately treated. Your healthcare provider will help you understand what your specific results mean for your health.

This content is for informational purposes only and does not constitute medical advice. Always consult a healthcare provider for diagnosis and treatment.

Ready to get tested? Order your test online → — no prescription needed.